AB1139 ASSOCIATION BETWEEN TRIGLYCERIDE‑GLUCOSE INDEX AND CAROTID ATHEROSCLEROSIS IN PATIENTS WITH PSORIATIC ARTHRITIS: A CROSS-SECTIONAL STUDY

Background The triglyceride-glucose (TyG) index, proposed as a surrogate marker for insulin resistance, appeared to be good indicator of clinically overt cardiovascular events and subclinical atherosclerosis in general population. Objectives We aimed investigate the correlation TyG index with atherosclerotic risk among patients psoriatic arthritis (PsA). Methods This cross-sectional study included 165 consecutive PsA receiving carotid ultrasonography integrated calculated ln [fasting triglycerides (mg/dL)×fasting glucose (mg/dL)/2]. Logistic regression models were applied analyze association continuous variables tertiles artery plaque. Results Overall, had substantially higher than those without (8.82±0.50 vs. 8.54±0.55, p=0.002). frequency was increased increases tertiles, showing 14.8%, 34.5%, 44.6% tertile 1, 2 3, respectively (p=0.003). Multivariate logistic analyses showed that each 1-unit increase significantly associated prevalent (unadjusted OR 2.65 [1.39-5.05]; fully-adjusted 2.69 [1.02-7.11]). Compared 1 unadjusted occurrence 4.64 (1.85-11.60) 5.10 (1.54-16.93) 3. Similarly, plaque observed increasing 3.11 [1.54-6.26]; 3.61 [1.15-11.38]) or 3 10.20 [2.83-36.82]; 17.89 [2.88-111.11]). Additionally, provided incremental predictive capacity beyond established factors, shown by an discrimination ability (all P < 0.001). Conclusion positively correlated burden patients, independent traditional factors psoriatic-related factors. These findings suggest may promising Figure 1. level arthritis, stratified (CA), (CAP). REFERENCES: NIL. Acknowledgements: Disclosure Interests None Declared.